| 2D Structure | |
| CID | 62920 |
| IUPAC Name | [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate;hydrochloride |
| InChI | InChI=1S/C22H26N2O4S.ClH/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;/h5-12,20-21H,13-14H2,1-4H3;1H/t20-,21+;/m1./s1 |
| InChI Key | HDRXZJPWHTXQRI-BHDTVMLSSA-N |
| Canonical SMILES | None |
| Isomeric SMILES | None |
| Molecular Formula | C22H27ClN2O4S |
| Molecular Weight | 451.0 |
| synonyms | ['Diltiazem hydrochloride', '33286-22-5', 'Diltiazem HCl', 'Adizem', 'Dilzem', 'Dilzene', 'Masdil', 'Altiazem', 'Deltazen', 'Diladel', 'Dilpral', 'Dilrene', 'Tildiem', 'Zilden', 'Cardizem CD', 'Cardizem LA', 'Britiazim', 'Dilacor', 'Diltzac', 'Cardizem SR', 'Cartia XT', 'Taztia XT', 'Viazem XL', 'Cartia', 'RG 83606', 'TAZTIA', 'Tiazac extended release', 'Slozem', 'OLH94387TE', 'NSC-759576', 'RG-83606', 'DTXSID8040147', 'CHEBI:645509', 'Calazem', 'Kentiazem', 'Tiamex', 'Optil', 'Calcicard cr', 'Dilcardia sr', 'Dilcardia xl', 'Disogram sr', 'Adizem-sr', 'Adizem-xl', 'Kenzem sr', 'Zildil sr', 'Bi-carzem sr', 'Bi-carzem xl', 'Diltiazem HCI', 'Matzim LA', 'Diltiazem HCl CD', 'Angiozem 60', 'Retalzem 60', 'Angiozem cr 90', 'Diltiazem HCL ER', 'Tildiem ret 90', '2-((2S,3S)-3-(acetyloxy)-2-(4-methoxyphenyl)-4-oxo-3,4-dihydro-1,5-benzothiazepin-5(2H)-yl)-N,N-dimethylethanaminium chloride', '2-[(2S,3S)-3-(acetyloxy)-2-(4-methoxyphenyl)-4-oxo-3,4-dihydro-1,5-benzothiazepin-5(2H)-yl]-N,N-dimethylethanaminium chloride', 'Angitil sr 90', 'Horizem sr 60', 'Horizem sr 90', 'Angiozem cr 120', 'Tildiem ret 120', 'Dilzem sr 60', 'Dilzem sr 90', 'Adizem-60', 'Angitil sr 120', 'Angitil sr 180', 'Angitil xl 240', 'Angitil xl 300', 'Horizem sr 120', 'Tildiem la 200', 'Tildiem la 300', 'Zemtard 120 xl', 'Zemtard 180 xl', 'Zemtard 240 xl', 'Zemtard 300 xl', 'Optil sr 90', 'Dilzem sr 120', 'Dilzem xl 120', 'Dilzem xl 180', 'Dilzem xl 240', 'Zemret 180 xl', 'Zemret 240 xl', 'Zemret 300 xl', 'Slozem 120', 'Slozem 180', 'Slozem 240', 'Uard 120xl', 'Uard 180xl', 'Uard 240xl', 'Uard 300xl', 'Optil sr 120', 'Optil sr 180', 'Optil xl 240', 'Optil xl 300', 'TIADYLT ER', 'RefChem:55023', 'DTXCID6020147', 'Diltiazem Hydrochloride Extended Release', 'Diltiazem Hydrochloride Extended-release', 'DILTIAZEM HYDROCHLORIDE IN DEXTROSE 5%', 'Diltiazem Hydrochloride Extended-Release Tablets', '(2S,3S)-5-(2-(Dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate monohydrochloride', 'Dilacor xr', '(+)-cis-Diltiazem hydrochloride', 'Cardizem', 'Tiazac', 'CRD-401', 'Lacerol', 'Mono-Tildiem', 'Bi-Tildiem', 'Diltiazem (hydrochloride)', 'Cardil', 'Dilren', 'MFCD00069252', 'diltiazem.hcl', '(2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate hydrochloride', '38411-61-9', 'Dilt-cd', '103532-26-9', 'Diltiazem HCl (Tiazac)', '[(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate;hydrochloride', 'MLS000028432', '(+)-5-(2-(Dimethylamino)ethyl)-cis-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate (ester) monohydrochloride', '(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride', 'Dilzicardin', 'Anginyl', 'Angitil', 'Angizem', 'Calcicard', 'Calnurs', 'Cardiazem', 'Cirilen', 'Citizen', 'Clarute', 'Corazet', 'Dilatam', 'Dilatame', 'Dilcard', 'Dilgard', 'Dilicardin', 'Diltahexal', 'Diltelan', 'Diltiasyn', 'Diltikor', 'Diltime', 'Dinisor', 'Dodexen', 'Entrydil', 'Farmabes', 'Gadoserin', 'Helsibon', 'Incoril', 'Kaltiazen', 'Levozem', 'Longazem', 'Lytelsen', 'Metazem', 'Miocardie', 'Oxycardil', 'Pazeadin', 'Pentilzeno', 'Poltiazem', 'Presoken', 'SMR000058375', 'Tilazem', 'Trumsal', 'Ziruvate', 'Bruzem', 'Carzem', 'Diatal', 'Dilfar', 'Dilsal', 'Diltam', 'Diltan', 'Doclis', 'Dyalac', 'Etizen', 'Etyzen', 'Herben', 'Kardil', 'Myonil', 'Slozen', 'Tiadil', 'Tiaves', 'Ubicor', 'Zildem', 'Carex', 'Coras', 'Dazil', 'Dilem', 'Dilso', 'Hesor', 'Tazem', 'Apo-diltiazem', 'Iski', 'Altiazem Retard', 'Cardizem Retard', 'Diltiazem Merck', 'Diltiazem Stada', 'Diltiazem Verla', 'Diltiazem-Mepha', 'Cardil Retard', 'Dil-Sonaramia', 'Diltiazem-Isis', 'Dilzem Retard', 'Dinisor Retard', 'Myonil Retard', 'Novo-Diltazem', 'Syn-Diltiazem', 'Tildiem Retard', 'Diltiazem Basics', 'Diltiazem-Cophar', 'Uni Masdil', 'WL Diltiazem', 'Altiazem RR', 'Diltiazem AWD', 'Diltiazem GNR', 'Diltiazem MSD', 'Diltiazem-GRY', 'Cirilen AP', 'Diltiazem Henning', 'Diltiazem UPSA', 'Tildiem CR', 'Tildiem LA', 'M01693', 'Adizem-CD', 'Diltan SR', 'Diltiazem Eu Rho', 'Dilzem RR', 'Viazem SR', 'C22H27ClN2O4S', 'Herbesser 60', '(2S-cis)-3-Acetoxy-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride', '[(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate;hydron;chloride', '1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride, (+)-cis-', 'Herbesser 90 SR', 'Tilazem 90', 'Diltiazem chloridrate', 'Dilatam 120', 'Tilazem AS 60', 'Tilazem AS 90', 'Dilzereal 90 Retard', 'Herbesser 180 SR', 'Dolizem', 'Iski-90 SR', 'Dilt-XR', '1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, hydrochloride (1:1), (2S,3S)-', 'Dodexen A.P.', 'Presokin A. P.', 'SR-01000003042', 'EINECS 251-443-3', 'Dilacor XR Extended Release Capsules', 'UNII-OLH94387TE', 'Milptin', 'Carzen', 'DOV diltiazem', 'Uni-Masdil', 'RG 83606 HCl', 'Cardizem XL', 'Tiazac XC', 'CRD 401', 'Cardizem (TN)', 'Prestwick_176', 'EINECS 253-918-0', 'Dilacor XR (TN)', 'Cartia XT (TN)', 'Opera_ID_79', 'Diltiazem hydrochloride [USAN:USP:JAN]', 'Dilt-CD (TN)', '(+)-5-(2-(dimethylamino)ethyl)-cis-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ester monohydrochloride', '(+)-cis-Diltiazem HCl', '33286-22-5 (HCl)', 'Diltiazem hydrochloride CRS', 'CHEMBL1697', 'SCHEMBL15457', 'MLS001148257', 'MLS002222179', 'DILTIAZEM HCL [VANDF]', 'orb1310926', '(+)-cis-Diltiazem hydrochlorid', 'Diltiazem for system suitability', 'SCHEMBL20394103', 'SLV-324', 'VEN-307', 'HMS1568K10', 'MSK10059', 'DILTIAZEM HYDROCHLORIDE [MI]', 'Tox21_500327', 'BNP-32762', 'Diltiazem (hydrochloride) (Standard)', 'Diltiazem for system suitability CRS', 'Diltiazem hydrochloride (JP18/USP)', 'DILTIAZEM HYDROCHLORIDE [JAN]', 'EBC-07790', 'HY-14656R', 's1865', 'DILTIAZEM HYDROCHLORIDE [USAN]', 'AKOS015961992', 'CCG-220134', 'CCG-221631', 'DILTIAZEM HYDROCHLORIDE [MART.]', 'DILTIAZEM HYDROCHLORIDE [VANDF]', 'FD22157', 'KS-5089', 'LP00327', 'NC00558', 'NSC 759576', 'DILTIAZEM HYDROCHLORIDE [USP-RS]', 'DILTIAZEM HYDROCHLORIDE [WHO-DD]', 'NCGC00093768-01', 'NCGC00261012-01', '(2S,3S)-(+)-3-Acetoxy-2,3-dihydro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride', '1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-, monohydrochloride, cis-(+)-', 'AC-15189', 'AC-32469', 'AS-13703', 'BD166408', 'cis-(1)-3-Acetoxy-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride', 'HY-14656', 'SY009752', '(+)-cis-Diltiazem Hydrochloride, >/=98%', 'DB-257619', 'D3662', 'DILTIAZEM HYDROCHLORIDE [EP IMPURITY]', 'DILTIAZEM HYDROCHLORIDE [ORANGE BOOK]', 'EU-0100327', 'NS00075848', 'ST50320016', 'SW196487-3', 'DILTIAZEM HYDROCHLORIDE [EP MONOGRAPH]', 'BIM-0050315.0001', 'D 2521', 'D00616', 'DILTIAZEM HYDROCHLORIDE [USP MONOGRAPH]', 'Diltiazem, Hydrochloride - CAS 33286-22-5', 'EN300-123531', 'F20448', '(+)-cis-Diltiazem hydrochloride, >=99% (HPLC)', 'SR-01000075327', 'SR-01000003042-2', 'SR-01000003042-4', 'SR-01000075327-1', 'Diltiazem.HCl, 1mg/ml in Acetonitrile (as free base)', 'Q27105183', 'Z1551967090', 'Diltiazem Hydrochloride 1.0 mg/ml in Acetonitrile (as free base)', 'Diltiazem hydrochloride, European Pharmacopoeia (EP) Reference Standard', 'Diltiazem hydrochloride, United States Pharmacopeia (USP) Reference Standard', 'Diltiazem for system suitability, European Pharmacopoeia (EP) Reference Standard', '(2S,3S)-(+)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one', '(2S,3S)-5-(2-(DIMETHYLAMINO)ETHYL)-2-(4-METHOXYPHENYL)-4-OXO-2,3,4,5-TETRAHYDROBENZO[B][1,4]THIAZEPIN-3-YL ACETATE HCL', '(2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-ylacetatehydrochloride', '(2S,3s)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride (1:1)', '(2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate--hydrogen chloride (1/1)', '(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2H,3H-benzo[b]1,4 -thiazaperhydroepin-3-yl acetate, chloride', '(2S,cis)-3-(Acetyloxy)-5-[(2-dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride', 'Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester; hydrochloride', 'cis-(+)-3-acetoxy-2,3-dihydro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5H)-one hydrochloride'] |
From Pubchem